Improved transdermal delivery of cetirizine hydrochloride using polymeric microneedles
نویسندگان
چکیده
منابع مشابه
Microneedles-Mediated Transdermal Delivery
The objective of the present study was to evaluate the potential of hollow microneedles for enhancing the transdermal delivery of Bovine Serum Albumin (MW~66,000 Da)-Fluorescein Isothiocyanate (BSA-FITC) conjugate, a hydrophilic large molecular compound. Moreover, the effect of different formulations was evaluated. The series of binary mixtures composed of propylene glycol (PG) and pH 7.4 phosp...
متن کاملCoated microneedles for transdermal delivery.
Coated microneedles have been shown to deliver proteins and DNA into the skin in a minimally invasive manner. However, detailed studies examining coating methods and their breadth of applicability are lacking. This study's goal was to develop a simple, versatile and controlled microneedle coating process to make uniform coatings on microneedles and establish the breadth of molecules and particl...
متن کاملMicroneedles for transdermal drug delivery.
The success of transdermal drug delivery has been severely limited by the inability of most drugs to enter the skin at therapeutically useful rates. Recently, the use of micron-scale needles in increasing skin permeability has been proposed and shown to dramatically increase transdermal delivery, especially for macromolecules. Using the tools of the microelectronics industry, microneedles have ...
متن کاملA review of the microneedles for transdermal drug delivery
Microneedles consist of micron-sized projections similar to needles. They are capable of piercing through the stratum corneum and increase the permeation of active ingredients. Besides active pharmaceutical ingredients, microneedles can also deliver cosmetic agents, biotherapeutics like insulin and vaccines and also are used in diagnostic purposes. This article examines the types of microneedle...
متن کاملFiberoptic Microneedles for Transdermal Light Delivery
Shallow light penetration in tissue has been a technical barrier to the development of photothermal therapies for cancers in the epithelial tissues and skin. This problem can potentially be solved by utilizing minimally invasive probes to deliver light directly to target areas potentially >2 mm deep within tissue. To develop this solution, fiber optic microneedles capable of delivering light fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: DARU Journal of Pharmaceutical Sciences
سال: 2019
ISSN: 2008-2231
DOI: 10.1007/s40199-019-00301-3